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Autoimmune Disease have
become the number one disease process today! In the whole world.
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Prozac
might cure "lazy eye", scientists say
By Ben Hirschler
LONDON (Reuters) -
Prozac, the popular
antidepressant,
might also be an
effective treatment
for adults with a
"lazy eye",
according to new
research.
A team of Italian
and Finnish
scientists said on
Thursday that the
medicine helped
correct the eyesight
of rats whose vision
had been impaired in
early development
and it could well do
the same for humans.
The medicine
appears to work by
returning neurons in
the adult brain to a
more "plastic" state
normally only seen
in youth. This
allows the visual
perception system to
develop its proper
connections between
the eye and the
brain.
The discovery
could also help
explain exactly how
antidepressants help
regulate mood in
depressed patients,
by suggesting brain
plasticity is a key
part of the process.
Prozac was
initially introduced
by U.S. drugmaker
Eli Lilly and Co in
1987 and belongs to
a class of compounds
called selective
serotonin reuptake
inhibitors (SSRIs).
It is now off patent
and widely available
generically as
fluoxetine.
Jose Fernando
Maya Vetencourt from
Scuola Normale
Superiore in Pisa
and colleagues
intend to go on to
study the drug's
curative properties
on human eyesight,
though definitive
clinical trial plans
have yet to be
developed.
"It will take a
couple of years,
maybe more," he told
Reuters.
Amblyopia,
commonly known as
"lazy eye", is the
most frequent cause
of visual impairment
in childhood and
affects 2 to 3
percent of children,
according to the
U.S. National Eye
Institute.
Unless it is
successfully
treated, it usually
persists into
adulthood. Treatment
involves making the
child use the weaker
eye, either by
applying an eye
patch or by putting
drops in the
stronger eye to
temporarily blur the
vision.
There is no proven
treatment for
adults.
Vetencourt said
the ability of
Prozac and perhaps
other SSRIs to
return neurons to a
more plastic state
could, in theory,
mean they might also
have a role in other
neurological
disorders in which
synaptic plasticity
was compromised,
including
Alzheimer's disease.
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Matching treatment settings,
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functioning. Participation in self-help
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