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NEW ORLEANS
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The results of a much-watched study comparing stents and
drugs were revealed at a Boston Scientific meeting Sunday
night. As most experts on both sides of the safety debate
expected, the study, COURAGE, showed no reduction in heart
attacks and deaths for patients who got a stent compared to
those who didn't.
Shares of Boston Scientific (nyse:
BSX -
news -
people ), which makes the most popular stent, fell more than
8% to $14 on the news. Shares of rival Johnson & Johnson
(nyse:
JNJ -
news -
people ) fell 1% to less than $59.93 on the news. The full
results will be available at 2 p.m. EST Monday.
The results were previewed two weeks ago by Forbes.com (see:
Study Could Hurt Stent Sales). A recap of that story
follows.
The 2,300-patient study, COURAGE, looks at two different ways
of treating patients with angina, the crushing chest pain that
results when the heart is not getting enough blood. Some
patients were treated with angioplasty, a procedure in which an
artery is opened with a balloon and then propped with a stent--a
wire mesh tube. After that, they also received heart medicines,
as needed. Others got the best medicines available, but did not
undergo a procedure to open their arteries.
Drug-coated stents are too new to have been used much in
COURAGE, but so far they look no different in terms of
preventing heart attacks and deaths than existing treatments.
The results were expected to be presented tomorrow morning here
at the annual meeting of the American College of Cardiology.
Advocates of greater drug-coated stent use say that COURAGE
may not be a fair test.
"I wouldn't be surprised if COURAGE, as designed, is a
negative trial," Gregg Stone, director of cardiovascular
research and education at Columbia University Medical Center,
said two weeks ago. "The purpose of most stent procedures in
patients with stable angina is to relieve chest pain and improve
exercise capacity and quality of life."
But others will likely argue that the study should lead to a
decrease in the use of stents. In an editorial in a recent issue
of the journal Circulation, Spencer B. King, a noted
interventional cardiologist at Fuqua Heart Center in Atlanta,
wrote that he was unsure patients would opt for stents if they
knew the devices would not prevent heart attacks and deaths.
"How many patients have interventions in which the only
expectation is to reduce the use of nitroglycerin or to walk a
bit faster?" King asked in his editorial. "Most patients
anticipate a better prognosis and might opt for an extended
course of medical therapy if they believe they are not putting
their life at excess risk."---------
------------------------------------------------------------------------CIDPUSA
recommends that you and your loved ones do not under go the
stent procedure. We offer alternative
treatments for this and management and prevention of
inflammation which is the real culprit in heart disease.
Dr .Khan
www.cidpusa.org
www.cidpusa.org/P/ivig.htm
http://www.cidpusa.org/disease.html
http://www.cidpusa.org/Lahore.html
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